Ujeedada: Si loo barto saameynta Agkistrodon acutus venom tumor suppressor part I (AAVC-I) ee xakameynta faafinta iyo apoptosis ee kansarka sambabada bini'aadamka A549 unugyada.Hababka: Heerarka xannibaadda ee AAVC-I ee kala duwanaansho kala duwan oo ku saabsan unugyada A549 ee 24h iyo 48h ayaa lagu qiyaasay habka MTT;HE midabaynta iyo midabka Hoechst 33258 fluorescence ayaa loo isticmaalay in lagu eego apoptosis ka morphology;Muujinta borotiinka bax waxaa lagu ogaaday immunohistochemistry.Natiijooyinka: MTT waxay muujisay in AAVC-I ay joojin karto faafinta unugyada A549 waqti ku-tiirsanaan iyo hab ku-tiirsanaan;Ka dib daaweynta AAVCI ee saacadaha 24, pyknosis nukliyeerka, hyperchromatic nukliyeerka iyo unugyada apoptotic ayaa lagu arkay mikroskoob;Immunohistochemistry waxay muujisay in celceliska cufnaanta indhaha ay kor u kacday korodhka feejignaanta daroogada, taas oo muujinaysa in muujinta borotiinka bax si isku mid ah loo habeeyay.Gabagabo: Qaybta Antitumor I ee Agkistrodon acutus venom waxay joojin kartaa kansarka sanbabada bini'aadamka ee unugyada A549 waxayna keeni kartaa apoptosis, taas oo laga yaabo inay la xiriirto kor u qaadida qaanuunka hadalka bax.
Waqtiga boostada: Jan-16-2023