Sababtoo ah daawada dhaqameed ee Shiinaha waxay aaminsan tahay in ay ka tirsan tahay qaybta "hilibka iyo walxaha dhiigga", aad ayaa loo qiimeeyaa.Daawo dhaqameedka Shiinaha ee xoolaha sunta ah ayaa door muhiim ah ka ciyaara cilmi baarista iyo ka faa'iidaysiga daawooyinka dhaqameed.Si kastaba ha noqotee, hadda, waxaa jira cilmi-baaris yar oo ku saabsan qaybaha gaarka ah ee firfircoon iyo habka ficilka ee xayawaanka sunta ah ee daawada dhaqameed ee Shiinaha ee Shiinaha.Caqabadda ugu weyni waa in qaybaha ay ka kooban yihiin ay adag yihiin in la kala saaro oo la nadiifiyo, ayna adag tahay in la aqoonsado dhismihiisa.Lai Ren, Xiong Yuliang, Zhang Yun, Xiao Changhua, Wang Wanyu iyo xubno kale oo ka mid ah kooxda cilmi-baarista ee Kunming Institute of Zoology, Akademiyada Shiinaha ee Sayniska ayaa muddo dheer bartay saldhigga walxaha iyo habka waxtarka daawada dhaqameed ee Shiinaha ee xayawaanka sunta ah, la aasaasay maktabad khayraad kelli firfircoon oo u dhiganta, horumariyo dawooyin badan oo cusub, oo si tartiib tartiib ah loo aasaasay "nidaamka tignoolajiyada macdanta la beegsaday oo ka mid ah qaybaha functional ee dawooyinka dhaqanka Shiinaha ee xayawaanka sunta ah oo ku salaysan xeeladaha badbaadada noole".Tilmaamaha nidaamkan tignoolajiyada ayaa ah: 1) hal-abuurnimo aragtiyeed: qaadashada istiraatiijiyadda badbaadada ee xayawaanka sunta ah sida hagitaan aragtiyeed si loo sahamiyo qaybaha shaqada;2) Hal-abuurnimada farsamada: proteomics oo ay weheliso farmashiistaha ayaa loo isticmaalaa si loola socdo kala-soocidda iyo nadiifinta qaybaha shaqada;3) Hal-abuurnimo isku-dhafan: abuur nidaam tignoolajiyada macdanta ee bartilmaameedka ah oo loogu talagalay qaybaha shaqada ee xayawaanka sunta ah iyo dawooyinka Shiinaha ee dhaqameed ee ku saleysan xeeladaha badbaadada noolaha, caddeeya aasaaska agabka ee xeeladahooda badbaadada, iyo muujinta aasaaska agabka iyo habka shaqeynta ee daawooyinka dhaqameed ee Shiinaha.Iyada oo loo marayo nidaamkan farsamada, waxay aqoonsadeen xanuun joojinta, hemostasis, antithrombotic, hypotensive, anti-kansarka, ka hortagga bakteeriyada, anti-oxidation, rheumatic arthritis-ka xakameynta difaaca jirka iyo molecules kale ee firfircoon ee muhiimka ah waxay muujinayaan aasaaska alaabtan daawooyinkan si ay u xoojiyaan waxtarkooda. , oo si toos ah u caddeeya waxtarka noocan ah ee daawada dhaqameed ee Shiinaha ee heerka molecular;Isla mar ahaantaana, waxay sidoo kale aqoonsatay maaddooyinka qaar ee keena xasaasiyadda, dhiig-baxa iyo dhibaatooyinka kale ee la xiriira, iyada oo bixisa hagitaan loogu talagalay isticmaalka badbaadada leh ee alaabtan daawada.Shaqadan taxanaha ah waxa ay aasaas adag u dhigtay casriyaynta dawo dhaqameedka Shiinaha iyo cilmi baadhista iyo horumarinta dawooyinka cusub ee dawooyinka noocaan ah.Waxa ay heshay 30 shati-hal-abuur ah iyo 1 nooc oo utility ah, kaas oo soo saaray qiimo saynis, bulsho iyo dhaqaale oo wanaagsan, oo inta badan ka muuqda: 1) muujinta maaddooyinka gaarka ah ee waxtarka leh ee dawooyinkan Shiinaha dhaqameed ee heerka molecular.Waxay aqoonsadeen in ka badan 800 molecules functional maaddooyinkan daawooyinka (oo ay ku jiraan peptides antimicrobial, bradykinin, tachykinin, antithrombotic peptides, protease inhibitors, proteases, bombesin, peptides antioxidant, immunosuppressants, fosfolipase, melittin. maqaarka, neurotides, iwm). oo la falanqeeyay qaab-dhismeedkooda, bartilmaameedyada waxqabad iyo hababka;2) Aqoonsiga kooxaha molecular wax ku ool ah waxay bixisaa saldhig cilmiyaysan oo loogu talagalay samaynta, farsamaynta iyo isticmaalka heerarkan daawada dhaqameed ee Shiinaha;3) Aqoonsiga walxaha leh waxyeelada sunta ah sida xasaasiyadda dawooyinka dhirta Shiinaha waxay siinaysaa hab lagu kala saaro loogana saaro waxyeelada sunta ah iyo waxyeelada dawooyinka dhirta Shiinaha, waxayna bixisaa fikrado lagu ogaanayo iyo ka hortagga sumowga dhirta Shiinaha;4) Qaar ka mid ah molecules firfircoon ee ka soo jeeda sunta xayawaanka ayaa loo sameeyay dawooyin caafimaad ama ay ku jiraan horumarinta, oo ay ku jiraan cobra polypeptide neurotoxin polypeptide, agkistrodon acutus venom thrombin, vespid polypeptide, gadfly anti laren, oo dhashay 1972, cilmi-baare iyo kormeeraha dhakhtarka ee Machadka Kunming Zoology, Akadeemiyada Sayniska Shiinaha, ku guulaysta Sanduuqa Sayniska Qaranka ee Aqoonyahanada Da'da yar, oo soo bandhigay hibooyinka "Barnaamijka Hibada ee boqolka" ee Akademiyada Sayniska Shiinaha ee 2004. Laga bilaabo Janaayo 2014, 125 waraaqaha SCI ayaa la daabacay sida ugu horeysay ama qoraaga u dhigma, sida Proc Natl Acad Sci, Mol Cell Proteomics, Dhiig-karka, iwm;Lagu casuumay inuu noqdo ku xigeenka tifaftirayaasha J Venom Res;Waxay codsatay in ka badan 70 shati-hal-abuurnimo.Waxay qabatay barnaamijyada muhiimka ah ee Aasaaska Sayniska Dabiiciga ah ee Shiinaha, Sanduuqa Sayniska Qaranka ee Aqoonyahannada Da'da yar ee Sharafta leh, Barnaamijka 973 ee Wasaaradda Sayniska iyo Teknolojiyadda, barnaamijka ugu weyn ee daahfurka daroogada cusub, iyo barnaamijyada jihaynta ee Akadeemiyada Shiinaha ee Sayniska.Waxay si isdaba joog ah ugu guulaysatay Abaalmarinta Hal-abuurka Farsamada Qaranka (2013, darajada koowaad), Abaalmarinta Sayniska Dhallinyarada ee Shiinaha iyo Tignoolajiyada (2011), Abaalmarinta Sayniska Nolosha Tan Jiazhen (2010) iyo sharafyo kale.Thrombotic polypeptide, centipede polypeptide, iwm;5) Waxa aanu samaynay habab lagu daweeyo sunta abeesada iyo sunta shinnida, anagoo bixinayna habab farsamo oo wax ku ool ah oo lagu daweeyo bukaanka sunta abeesada iyo sunta shinnida.Machadka Kunming ee Sayniska, Akadeemiyada Sayniska ee Shiinaha ayaa ku guuleystay natiijooyin cilmi baaris oo cajiib ah oo ku saabsan dhinacyada la xiriira: sannadihii la soo dhaafay, waxay daabacday in ka badan 200 oo waraaqo SCI ah, waxayna ku guuleysatay 4 abaalmarinnada koowaad ee gobolka iyo wasiirka iyo 6 abaalmarin labaad.2013, Machadka Kunming ee Xayawaanka, Akadeemiyada Sayniska Shiinaha ayaa ku guuleystay abaalmarinta labaad ee Abaalmarinta Tignoolajiyada Qaranka ee Mashruuca "Nidaamka Farsamada Farsamada Macdanta Jihada ee Qaybaha Waxqabadka ee Daawada Dhaqameedka Shiineeska ee Sunta ah ee ku salaysan Istaraatiijiyada Badbaadinta Nafleyda".
Waqtiga post: Dec-09-2022